Scientific interests
- Biochemistry of cancer, biochemical mechanisms of hypoxia, biochemistry of type 2 diabetes, molecular mechanisms of signaling systems, in vivo animal models, preclinical research
Education
Institution
91视频
Faculty
Biology/Biochemistry
Date
-
Degree name
Masters
Institution
91视频
Faculty
Biology/Biochemistry
Date
-
Degree name
Bachelor
Scientific Rank/degree
Institution
91视频
Date
2014
Degree name
Candidate
Specialty
Biological sciences
Scientific Supervisor
Ph.D, Professor, M.A. Davtyan
Research Topic
Influence of NO on the urea cycle
Language skills
English
袪褍褋褋泻懈泄
Work experience
Institution
Yerevan State University
Period of time
Rank/degree
Signal Transduction and Experimental Pathology Research group leader
Institution
Yerevan State University
Period of time
Rank/degree
assistant professor
Institution
91视频
Period of time
-
Rank/degree
Research group leader
Institution
91视频
Period of time
-
Rank/degree
Junior researcher
Participation in international conferences and seminars
-
Erasmus+ Staff Training week "Implementation and Development of Erasmus+ (KA 1+2)"
Saarland University
Germany
-
Modelling immunotherapy response and toxicity in cancer鈥 (IMMUNO-model) CA21135
Dublin City University
Ireland
Membership
Institution
The European Association for Cancer Research
Period of time
Institution
The Federation of the European Biochemical Societies
Period of time
Other information
Publications
Article
Elucidating the impact of Hypericum alpestre extract and L-NAME on the PI3K/Akt signaling pathway in A549 lung adenocarcinoma and MDA-MB-231 triple-negative breast cancer cells
2025
e0303736
Article
ALTERATIONS IN ARGINASE ACTIVITY, NITRIC OXIDE, AND MDA LEVELS IN BONE MARROW DURING DMBA-INDUCED BREAST CANCER IN RATS
2025
113-121
Article
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L-arginine
2024
1-21
Article
5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches
2024
1-16
Article
Royal Jelly鈥揗ediated Silver Nanoparticles Show Promising Anticancer Effect on HeLa and A549 Cells Through Modulation of the VEGFa/PI3K/Akt/MMP-2 Pathway
2024
1-11
Article
Anti-cancer effect of in vivo inhibition of nitric oxide synthase in a rat model of breast cancer
2023
261-275
Article
Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
2023
106396
Article
Screening revealed the strong cytotoxic activity of Alchemilla smirnovii and Hypericum alpestre ethanol extracts on different cancer cell lines
2023
12鈥22
Article
THE CYTOTOXIC PROPERTIES OF ALCHEMILLA SMIRNOVII EXTRACT ON THE HELA CANCER CELLS VIA DOWNREGULATION OF ARGINASE ACTIVITY
2023
238-247
Article
REGULATORY EFFECTS OF RUMEX OBTUSIFOLIUS AND HYPERICUM ALPESTRE EXTRACTS ON THE QUANTITY OF IL-2 IN IN VITRO AND IN VIVO CANCER MODELS
2023
248-257
Article
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats
2022
104763
Article
The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats
2021
103598
Article
NEW THERAPEUTIC APPROACHES IN BREAST ANTICANCER TREATMENT USING ARMENIAN HERBAL EXTRACTS
2021
32-38
Article
The potential therapeutic effect of NG-hydroxy-nor-L-arginine in 7,12-dimethylbenz(a)anthracene-induced breast cancer in rats
2019
1-10
Article
NG-諃曰源諓諘諗諐曰-諉請諓-L-员諓猿曰諉曰諉曰 諃员钥员請諕諏請諕諔諗员諈曰諉 员远源缘諔請諕怨諈請諕諉愿 7鈥12-源曰談缘怨曰约圆缘諉远员諉諒諓员諔缘諉請諑 越怨员諉諑员跃 员諏諉缘諒諉缘諓曰 钥諓跃諗员猿缘諅諄曰 諗员諅諔钥缘諅曰 論請諓諄员諓员諓员钥员諉 談請源缘约請諕談
2019
114-121
Article
The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer
2018
8696923,9
Article
THE CHANGE OF POLYAMINES AND NITRIC OXIDE QUANTITIES IN HUMAN BLOOD SERUM OF PROSTATE AND BLADDER CANCER
2017
125-132
Article
DIETHYLAMINE NONOate INFLUENCE ON RATS UREA CYCLE ENZYMES ACTIVITY AFTER AND BEFORE HYPOXIA
2016
15-19
Article
EFFECT OF HYPOXIA ON THE ACTIVITY OF UREA CYCLE ENZYMES
2014
13-16
Article
THE INFLUENCE OF NG -HYDROXY-L-ARGININE ON THE ACTIVITY OF THE UREA CYCLE ENZYMES
2014
113-117