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34-27
(060) 71-04-27
g.melikyan@ysu.am

Գագիկ Սուրենի Մելիքյան

Ֆարմացիայի ինստիտուտ
Ֆարմացիայի ԳՀ կենտրոն
Գիտական աշխատող

Անձնական տվյալներ

Ծննդյան տարեթիվ
1945

Հրապարակումներ

Հոդված
Efficient Synthesis and Biological Evaluation of 1,4-Disubstituted 3-Cyanopyridin-2(1H)-ones as Selective Inhibitors of the Post-Acid Activity of Mammalian 20S Proteasomes
L. V. Karapetyan
G. G. Tokmajyan
G. S. Melikyan
M. Bouvier-Durand
M. Reboud-Ravaux
T. H. Pham
2025
449-455
Հոդված
NEW C1 AND N5 DERIVATIVES OF CERPEGINE. SYNTHESIS AND ANTIBACTERIAL ACTIVITY STUDY
G.S. Melikyan
R.M. Hakobyan
H.V. Adunts
H.S. Attaryan
R.E. Muradyan
H.G. Arakelyan
N.A. Mirakyan
A.M. Davinyan
S.S. Mamyan
2025
35-47
Հոդված
SYNTHESIS OF NEW γ-LACTONE RING DERIVATIVES CONTAINING PYRIDINE AND TRICONDENSED SYSTEMS ( СИНТЕЗ НОВЫХ ПРОИЗВОДНЫХ γ-ЛАКТОННОГО КОЛЬЦА, СОДЕРЖАЩИХ ПИРИДИНОВЫЕ И ТРИКОНДЕНСИРОВАННИЕ СИСТЕМЫ )
R.M. Hakobyan
L.A. Kharatyan
S.S. Hayotsyan
H.S. Attaryan
G.S Melikyan
2024
28-40
Հոդված
Synthesis and Biological Activity of 4-Fluorophenylcyclohexyl(tetrahydropyranyl)methyl-Substituted Aryloxypropanolamines
G. S. Melikyan
A. A. Aghekyan
G. G. Mkryan
H. A. Panosyan
A. S. Tsatinyan
A. S. Grigoryan
H. V. Gasparyan
2023
756-763
Հոդված
Synthesis and Selected Transformations of New 2-Aminopyridine Derivatives Based on Furan-2(5H)-ones
Gagik S. Melikyan
Robert M. Hakobyan
Astghik A. Shahkhatuni
Hovhannes S. Attaryan
Armen G. Ayvazyan
2023
e202301183
Հոդված
Synthesis of Substituted 4-(Thiophen-2-yl)nicotinonitriles
G. S. Melikyan
R. M. Hakobyan
H. S. Attaryan
S. S. Hayotsyan
2020
356-360
Հոդված
Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition
Gagik Melikyan
Anna A. Hovhannisyan
Simon Hayek
Nicolas Pietrancosta
Rodolphe Alves de Sousa
Nassima Bekaddour
Laura Ermellino
Enzo Tramontano
Stephanie Arnould
Claude Sardet
Julien Dairou
Olivier Diaz
Vincent Lotteau
Sebastien Nisole
Jean-Philippe Herbeuval
Pierre-Olivier Vidalain
2020
111855
Հոդված
Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice
Gagik Melikyan
Yeranuhi Hovhannisyan
Nathalie Mougenot
Jacqueline Gao-Li
Bertrand Friguet
Denise Paulin
Zhenlin Li
Arnaud Ferry
Onnik Agbulut
2019
e0215821
Հոդված
Synthesis of pyridone-substituted furan-2(5H)-ones and their intramolecular cyclization to afford furo[3,4-f]isoquinolines
Gagik S. Melikyan
Robert M. Hakobyan
Sargis S. Hayotsyan
Hovhannes S. Attaryan
2019
1245-1250
Արտոնագիր
NOVEL 5-CYCLOPROPYL- [3,4-C]PYRIDINE-3,4(1H,5H)-DIONE 1,1’ SUBSTITUTED DERIVATIVES AND THEIR USES
MELIKYAN , Mr. Gagik
HAYEK, Mr. Simon
PIETRANCOSTA, Mr. Nicolas
HERBEUVAL, Mr. Jean-Philippe
ALVES DE SOUZA , Mr. Rodolphe
VIDALAIN , Mr. Pierre-Olivier
2019
Հոդված
Phenoxypropanolamine derivatives as selective inhibitors of the 20S proteasome b1 and b5 subunits
Gagik S. Melikyan
Anna A. Hovhannisyan
The Hien Pham
Dominique Bouvier
Xiao Tan
SiAmmar Touhar
Gevorg G. Mkryan
Ashot M. Dallakyan
Chahrazade El Amri
Michèle Reboud-Ravaux
Michelle Bouvier-Durand
2017
5172–5178
Գիտաժողովի նյութ
Synthesis of new3-pyridine substituted furan-2(5H)-ones
G. Melikyan
R. Hakobyan
S Hayotsyan
H. Attaryan
2017
114-115
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